Enabling Chemistry...
for Intractable Challenges
Our Purpose
Complex molecular architectures demand fundamental breakthroughs at the reaction mechanism level, delivering structural stability where conventional synthesis fails.
Bridging Theory and Deployment
Twelfth Vertex was founded at the intersection of computational molecular design and physical reaction execution. Our methodology ensures unprecedented target druggability in medicine and ultra-high-density energy storage materials.
We exist to bridge the gap between theoretical chemical breakthroughs and commercial-scale deployment, maintaining uncompromising standards of empirical validation and intellectual property protection.
World-class Research Facilities
Twelfth Vertex operates advanced laboratories for the creation on entirely-new materials. These include numerous fume hoods and equipment for creating and processing materials under inert conditions.
We recently opened a new laboratory housing two high-resolution nuclear magnetic resonance spectrometers, each equipped to analyze many different nuclei of interest.
Researchers at Twelfth Vertex have unparalleled experience and expertise in the field of mass spectrometry. We operate numerous instruments, including a new, ultra-high resolution mass spectrometer.






Synthetic Laboratories
Nuclear Magnetic Resonance Spectroscopy
Ultra-high Resolution Mass Spectrometry
Materials Characterization Laboratory


Twelfth Vertex operates a full suite of advanced analytical instrumentation, on par with those found only at top research universities.
Industry-Academic Partnerships


In addition to our in-house laboratories, Twelfth Vertex has partnered with both industry and top research universities to move our science forward.
Discuss a partnership to unblock your most challenging synthetic bottlenecks.
